Por eso la GF para llegar a un estado de transicin a menudo se denomina la energa de activacin E act. Los parmetro termodinmicos que determinan la rapidez de una reaccin, son los formacin de los estados de transicin de una reaccin. Es decir cualquier cosa que aumente la frecuencia o energa de colisin entre sustratos aumentare el ndice de la reaccin. Temperatura Al aumentar la temperatura, aumenta la energa cintica de las molculas, seguido de un aumento en su rapidez de movimiento, y por ende aumenta la frecuencia del choque mas energticos y productivos.

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