ALLETHRIN TOXICITY PDF

Allethrin: Alleviate, Pynamin. Containers of technical d-trans allethrin must bear the signal "Warning" 1. The purified d-trans-isomer of allethrin is more toxic to insects and is used for control of crawling insects in homes and restaurants 1. Allethrin is a synthetic duplicate of a component of pyrethrum. Pyrethrum is a botanical insecticide extracted from chrysanthemum flowers. Allethrin, the first synthetic pyrethroid, was introduced in , and is a mixture of several isomeric forms.

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Allethrin: Alleviate, Pynamin. Containers of technical d-trans allethrin must bear the signal "Warning" 1. The purified d-trans-isomer of allethrin is more toxic to insects and is used for control of crawling insects in homes and restaurants 1.

Allethrin is a synthetic duplicate of a component of pyrethrum. Pyrethrum is a botanical insecticide extracted from chrysanthemum flowers. Allethrin, the first synthetic pyrethroid, was introduced in , and is a mixture of several isomeric forms.

The most common form is a mixture of the trans- and cis-isomers. It is available in aerosol, coil, mat, dust and oil formulations. Aerosol and spray formulations of the purified d-trans- isomer of allethrin are also available. D-trans allethrin is usually combined with synergists such as piperonyl-butoxide 1.

Unless stated otherwise, information in this PIP refers to unpurified allethrin. Short-term dermal exposure to allethrin may cause itching, burning, tingling, numbness, a feeling of warmth, with no dermatitis 2. Exposure to large doses by any route may lead to nausea, vomiting, diarrhea, hyperexcitability, incoordination, tremors, convulsive twitching, convulsions, bloody tears, incontinence, muscular paralysis, prostration and coma 2.

Persons sensitive to ragweed pollen are at increased risk from exposure to allethrin 2. Allethrin is a central nervous system stimulant 2. Heavy respiratory exposure caused incoordination and urinary incontinence in mice and rats 2. The toxicity of allethrin varies with the amounts of different isomers present. Reproductive Effects No information was found. Mutagenic Effects Allethrin has been found to be mutagenic under certain conditions in strains of the bacterium Salmonella typhinurium 3.

However, 2 other tests of bioallethrin for mutagenicity DNA damage and reverse mutation were negative 5. Organ Toxicity Pyrethroids may cause adverse effects on the central nervous system. Long-term feeding studies have caused increased liver and kidney weights and adverse changes in liver tissues in test animals 2. Fate in Humans and Animals No information was found.

Allethrin degrades rapidly in the environment 5. Effects on Birds Allethrin is practically non-toxic to birds. Effects on Aquatic Organisms Allethrin is highly toxic to fish and aquatic invertebrates. The toxicity of allethrin in 27 species of warm and cold-water fish was measured.

The results ranged from an LC50 of 2. The LC50 for allethrin in stoneflies is 5. Fish sensitivity to the pyrethroids may be explained by their relatively slow metabolism and elimination of these compounds. The half-lives for elimination of several pyrethroids by trout are all greater than 48 hours, while elimination half-lives for birds and mammals range from 6 to 12 hours 6.

Effects on Other Animals Nontarget species At normal application rates, allethrin is slightly toxic to bees 1 , 5. Breakdown of Chemical in Surface Water In pond waters and in laboratory degradation studies, pyrethroid concentrations decrease rapidly due to sorption to sediment, suspended particles and plants. Microbial and photodegradation also occur 7. Breakdown of Chemical in Vegetation No information was found.

It may decompose when exposed to heat or light and it is incompatible with alkalis 2. Physical Properties:.

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Allethrin toxicity causes reproductive dysfunction in male rats.

Environ Toxicol. Epub Feb 9. Allethrin toxicity causes reproductive dysfunction in male rats. Madhubabu G 1 , Yenugu S 1. Pyrethroids are widely used for domestic and agricultural purposes and their use is increasing, especially in developing countries. Uncontrolled use of these insecticides resulted in their entry into the food chain thereby causing toxicity to different organ systems. Allethrin is one of the widely used pyrethroids, but its toxicological effects are underreported when compared to other pyrethroids.

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